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As well as gastrointestinal symptoms, may occur. Treatment of overdosage is essentially symptomatic and supportive. Atropine-like signs and symptoms-dry mouth; fixed, dilated pupils; flushing; etc.
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Promethazine green cough syrup the Institute for Safe Medication PracticesISMP recommend that parenteral administration of the drug be avoided and replaced by safer alternative therapies e. a type 3 serotonin5-HT3receptor promethazine green cough syrup such as ondansetron FDA states that subcutaneous or intra-arterial administration of promethazine hydrochloride is contraindicated.
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Promethazine Hydrochloride and Codeine Phosphate Oral Solution is a prescription medicine used in promethazine green cough syrup to temporarily treat cough and upper respiratory symptoms that you can have with allergies or a common cold.
Promethazine is an antihistamine. Tell your healthcare provider right away if you are pregnant or think you may be pregnant. Codeine is an opioid narcotic cough suppressant. Promethazine Hydrochloride and Codeine Phosphate Oral Solution contains 2 medicines, promethazine and codeine.
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Canada residents can call a provincial poison promethazine green cough syrup center. Do not share this medication with others. Sharing it is against the law. Symptoms of overdose may include: confusion, cold/clammy skin, fast/slow/irregular heartbeat, slow/shallow breathing, seizures, fainting, coma.
US residents can call their local poison control center at 1-800-222-1222.
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Promethazine injections are used when the oral route is not possible for example, with severe vomiting Suppositories are unwrapped and moistened with water before insertion into the rectum. Oral, rectal and injectable doses are similar.
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Promethazine green cough syrup Serious breathing problems. Promethazine HCl Oral Solution may cause drowsiness which may impair your ability to ride a bike, drive a car, or operate machinery. Promethazine HCl Oral Solution should not be used in patients with poor lung function such as chronic obstructive lung disease or breathing problems while sleeping sleep apnea.
Increased risk of seizures. This may be worsened if taken with alcohol or other drugs that also cause central nervous system CNS slowing such as sedatives, pain medicines, tranquilizers or certain drugs for depression. promethazine green cough syrup
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- Anagement: Reduce the usual dose of CNS depressants by 50% if starting methotrimeprazine until the dose of methotrimeprazine is stable. Methotrimeprazine may promethazine green cough syrup the CNS depressant effect of CNS Depressants.
- Promethazine green cough syrup Do not use a household teaspoon or tablespoon to measure this drug. Doing so could lead to the dose being too high. If there is none, ask the pharmacist for a device to measure this drug.
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POSTMARKETING CASES OF RESPIRATORY DEPRESSION, INCLUDING FATALITIES, HAVE BEEN REPORTED WITH USE OF Promethazine HYDROCHLORIDE ORAL SOLUTION IN PEDIATRIC PATIENTS LESS THAN 2 YEARS OF AGE. A WIDE RANGE OF WEIGHT-BASED DOSES OF Promethazine HYDROCHLORIDE ORAL SOLUTION HAVE RESULTED IN RESPIRATORY DEPRESSION IN THESE PATIENTS. Promethazine is contraindicated in comatose states, and in individuals known to be hypersensitive or to have had an idiosyncratic reaction to Promethazine or to other phenothiazines.
Antihistamines are contraindicated for use in the treatment of lower respiratory tract symptoms including asthma. Promethazine HYDROCHLORIDE ORAL SOLUTION SHOULD NOT BE USED IN PEDIATRIC PATIENTS LESS THAN 2 YEARS OF AGE Promethazine green cough syrup OF THE POTENTIAL FOR FATAL RESPIRATORY DEPRESSION.Promethazine about:
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Keep the medication in a place where others cannot get to it. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH.
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Codeine is subject to variability in metabolism based upon CYP2D6 genotype described below which can lead to an increased exposure to the active metabolite promethazine green cough syrup. Antihistamines and codeine are both contraindicated for use in the treatment of lower respiratory tract symptoms, including asthma Life-threatening respiratory depression and death have occurred in children who received codeine.
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When used before surgery, promethazine may be used the night before or just before the procedure and may be continued afterwards as directed. For motion sickness, the first dose of promethazine should be used 30 to 60 minutes before beginning travel.
For allergies, this medication may promethazine green cough syrup used once daily at bedtime to avoid being drowsy during the day.
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Convulsions may rarely occur. A paradoxical-type reaction has been reported in children receiving single doses promethazine green cough syrup 75 mg to 125 mg orally, characterized by hyperexcitability and nightmares. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensorplantar reflexes Babinski reflex Stimulation may be evident, especially promethazine green cough syrup children and geriatric patients.
Signs and symptoms of overdosage with promethazine hydrochloride range from mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and sudden death.
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Inform patients that chronic use of opioids, such as codeine, a component of Promethazine Hydrochloride and Codeine Promethazine green cough syrup Oral Solution, may cause reduced fertility. Advise women that breastfeeding is not recommended during treatment with Promethazine Hydrochloride and Codeine Phosphate Oral Solutionsee Use in Specific Populations 8.
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Children may be especially sensitive to this effect. Do not give this medicine to: Children younger than 18 years of age who have had surgery removal of tonsils or adenoids. As a result, there may be too much morphine in promethazine green cough syrup body and more side effects from morphine than usual.
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Patients receiving parenteral formulations should report persistent/worsening pain or promethazine green cough syrup at the injection site. IV formulations should be diluted to a concentration of 25 mg/mL or less.
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Promethazine is an H1 receptor blocking agent. Promethazine is a phenothiazine derivative which differs structurally from the antipsychotic phenothiazines by the presence of a branched side chain and no ring substitution.
It is thought that this configuration is responsible for its relative lack 1/10 that of chlorpromazine of dopamine antagonist properties. promethazine green cough syrup
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Use an effective form of birth control to keep from getting pregnant. If you are using this medicine for a long time, tell your doctor about any extra stress or anxiety in your life, including other health concerns and emotional stress.
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