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Ref A 45-year-old female developed massive crystalluria, gross hematuria, and acute anuric renal failure after 12 days of intravenous amoxicillin-clavulanate at a dose of 2 g amoxicillin 3 times daily (not available in the United States) The crystals were composed of amoxicillin trihydrate. epatic cholestasis and acute cytolytic hepatitis have been reported with amoxicillin use. Ref Renal side effects have rarely included crystalluria, hematuria, acute renal failure, and acute interstitial nephritis, often associated with fever, rash, and eosinophilia. ...
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